Pathophysiology of distributive shock in sepsis beyond vasoplegia

POCUSHemodynamicSeptic shock
Written By Frédéric Caruso

Septic shock is more than circulatory failure due to vasoplegia. It involves profound disturbances at microvascular, metabolic, neuroendocrine, myocardial and neural levels. This emphasises the need for integrative diagnostic strategies, new therapeutic approaches, and new forms of care targeting microcirculatory, metabolic, endocrine, myocardial and neural homeostasis to improve outcomes.


Reference

Highlighted paper

Thanks to the author.

Frédéric Caruso
Previous

ICU Management in 2050: Distributed Critical Care, Emerging Technologies and the Role of Artificial Intelligence
Next

Twenty-five years of septic shock hemodynamic resuscitation trials : a conceptual perspective